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Symbol Name ID |
Pdcd1lg2
programmed cell death 1 ligand 2 MGI:1930125 |
| Darker colors indicate more annotations |
| Mouse Phenotypes | decreased T cell proliferation |
insulitis |
increased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
increased CD8-positive, alpha-beta T cell number |
decreased IgG2a level |
increased IgG2a level |
increased IgM level |
abnormal CD8-positive, alpha-beta T cell physiology |
abnormal cytotoxic T cell physiology |
lymph node hyperplasia |
abnormal dendritic cell physiology |
abnormal dendritic cell antigen presentation |
abnormal cytokine secretion |
increased interferon-gamma secretion |
increased interleukin-2 secretion |
increased susceptibility to autoimmune diabetes |
increased susceptibility to parasitic infection |
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| Availability | Mouse Genotype | ||||||||||||||||||
| Pdcd1lg2tm1.1Lex/Pdcd1lg2tm1.1Lex | |||||||||||||||||||
| Pdcd1lg2tm1Dmp/Pdcd1lg2tm1Dmp | |||||||||||||||||||
| Pdcd1lg2tm1Shr/Pdcd1lg2tm1Shr | |||||||||||||||||||
| Pdcd1lg2tm2Shr/Pdcd1lg2tm2Shr | |||||||||||||||||||
| Pdcd1lg2tm3Shr/Pdcd1lg2tm3Shr | |||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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